BDBM50268223 2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethanone::CHEMBL521155

SMILES Nc1ncnc2n(CC(=O)c3c[nH]c4ccccc34)cnc12

InChI Key InChIKey=FJJRVJOTLKWVLC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50268223   

TargetEpidermal growth factor receptor(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268223(2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268223(2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268223(2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268223(2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268223(2-(6-Amino-9H-purine-9-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of ERBB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed