BDBM50268247 8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione::CHEMBL488541

SMILES CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(CCc2ccccc2)CC1

InChI Key InChIKey=UOSGXUGKZYRNKU-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50268247   

TargetAdenosine receptor A2b(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi:  7.51nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi:  271nMAssay Description:Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi:  681nMAssay Description:Displacement of [3H]MSX-2 from rat brain striatum adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CCPA from rat brain cortex adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268247(8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-p...)
Affinity DataIC50:  10.9nMAssay Description:Antagonist activity at adenosine A2B receptor in human Jurkat T cells assessed as inhibition of NECA-induced increase in intracellular calcium concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed