BDBM50268310 CHEMBL4069479

SMILES O=C1COc2ccc(CNC(=O)c3nc4scc(-c5ccc(C(F)(F)F)cc5)c4c(=O)[nH]3)cc2N1

InChI Key InChIKey=GUEZUXNRTRXDAO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268310   

TargetCollagenase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268310BDBM50268310(CHEMBL4069479)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Notre Dame

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268310BDBM50268310(CHEMBL4069479)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed