BDBM50269194 CHEMBL4059590

SMILES COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC[C@H](NC(=O)/C=C/c1cc(Cl)ccc1-n1cnnn1)c1nc-2c[nH]1

InChI Key InChIKey=YMBMZGJMSVVTRS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269194   

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269194BDBM50269194(CHEMBL4059590)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269194BDBM50269194(CHEMBL4059590)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed