BDBM50269392 CHEMBL4068447
SMILES Cc1csc2c(nc(Cl)nc12)-n1nc(Nc2ccc(cc2)N2CCN(CC2)C2CC3CCC2C3)nc1N
InChI Key InChIKey=HLRDOMFIYHUBLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50269392
Affinity DataEC50: 170nMAssay Description:Inhibition of Axl in human HeLa cells assessed as reduction in AKT phosphorylation at Ser 473 residues pre-incubated for 1 hr before preclustered ant...More data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Inhibition of VEGF stimulated VEGFR2 phosphorylation at Y165 residues in HUVEC preincubated for 1 hr followed by VEGF addition measured after 5 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal GST-tagged human Axl (464 to 885 end residues) cytoplasmic domain expressed in baculovirus expression system using HS1 pepti...More data for this Ligand-Target Pair