BDBM50269413 CHEMBL4093559

SMILES C[C@@H]1CN(CCN1c1nc(cc(=O)n1C)-c1ccncn1)c1ccc(cc1)C#N

InChI Key InChIKey=IOCOIAHOBCNOFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269413   

TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269413(CHEMBL4093559)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269413(CHEMBL4093559)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269413(CHEMBL4093559)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed