BDBM50269777 CHEMBL4102419

SMILES O[C@]1(Cc2cc(on2)-c2cn[nH]c2)CC[C@H](Cc2ccccc2)CC1

InChI Key InChIKey=JVPOHQBKCRIEMN-MOBUCQHHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269777   

TargetGlutamate receptor ionotropic, NMDA 2B(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269777(CHEMBL4102419)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269777(CHEMBL4102419)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]-ifenprodil from NR2B in Wistar rat brain membrane after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed