BDBM50269921 3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-quinuclidinol::CHEMBL478348

SMILES CCOC(=O)Cc1ccc(C#CC2(O)CN3CCC2CC3)cc1

InChI Key InChIKey=YWKVMGDEOUPQGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269921   

TargetSqualene synthase(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269921BDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269921BDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50: 970nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed