BDBM50270302 3-[7'-(Methoxy)-napht-2'-yl]-quinuclidine-2-ene::CHEMBL478981

SMILES COc1ccc2cc(C3=CN4CCC3CC4)ccc2c1

InChI Key InChIKey=KZWBNNXTWZPPPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270302   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270302BDBM50270302(3-[7'-(Methoxy)-napht-2'-yl]-quinuclidine-2-ene | ...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270302BDBM50270302(3-[7'-(Methoxy)-napht-2'-yl]-quinuclidine-2-ene | ...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed