BDBM50270321 3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene::CHEMBL453439

SMILES C1=C(c2ccc(OCc3ccccc3)cc2)C2CCN1CC2

InChI Key InChIKey=OKNMXSHKBLYYKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270321   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270321BDBM50270321(3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270321BDBM50270321(3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene ...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed