BDBM50270464 CHEMBL4076203

SMILES CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)Cn2cc(-c3ccc(-c4ccccc4)cc3)nn2)OC(C(=O)O)=C[C@@H]1O

InChI Key InChIKey=MOBLYRFFBQZZKA-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50270464   

TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataKi:  260nMAssay Description:Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataKi:  280nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 520nMAssay Description:Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 700nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using GM3 as substrate preincubated for 15 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using GM3 as substrate preincubated for 15 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human N-terminal MBP-fused NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of human N-terminal MBP-fused NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human NEU1 expressed in HEK293 cells using 4-MUNANA as substrate preincubated with compound for 0.25 hrs followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270464BDBM50270464(CHEMBL4076203)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human CathA-IRES-6His-tagged NEU1 expressed in HEK293T cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed