BDBM50270758 CHEMBL4127486

SMILES CCOc1cccc(c1)-c1nc(SCC(=O)Nc2nc(cs2)-c2cc(Cl)c(N)c(Cl)c2)[nH]c(=O)c1C#N

InChI Key InChIKey=RIMCGTVMTSKNSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270758   

TargetBeta-secretase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50270758(CHEMBL4127486)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed