BDBM50271122 CHEMBL4128728

SMILES CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2n(C)ncc2c1

InChI Key InChIKey=LYXWGAYLUFGHSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271122   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271122(CHEMBL4128728)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 20 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50271122(CHEMBL4128728)
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed