BDBM50271229 CHEMBL3719209

SMILES CC(C)n1nc(cc1C1CCN(CC1)C1COC1)-c1cnc2[nH]cc(F)c2c1

InChI Key InChIKey=NJYKWCYJGYJRDZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271229   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Wuxi Apptec

Curated by ChEMBL

LigandBDBM50271229(CHEMBL3719209)Copy SMILESCopy InChI

Affinity DataKi:  96nMAssay Description:Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetMitogen-activated protein kinase kinase kinase 12(Human)
Wuxi Apptec

Curated by ChEMBL

LigandBDBM50271229(CHEMBL3719209)Copy SMILESCopy InChI

Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-bas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL