BDBM50271341 CHEMBL4128493::US12012467, Compound DI-32

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCCc2ccccc12

InChI Key InChIKey=VFDJJOWVDLNRRA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271341   

TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271341(CHEMBL4128493 | US12012467, Compound DI-32)
Affinity DataKi:  84nMAssay Description:Displacement of (S)-N1-((19S,22S)-26-Amino-19-carbamoyl-1-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1,13,21-trioxo-5,8,11-tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271341(CHEMBL4128493 | US12012467, Compound DI-32)
Affinity DataIC50: 461nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271341(CHEMBL4128493 | US12012467, Compound DI-32)
Affinity DataIC50: 550nMAssay Description:Displacement of (S)-N1-((19S,22S)-26-Amino-19-carbamoyl-1-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1,13,21-trioxo-5,8,11-tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed