BDBM50271975 CHEMBL4129817
SMILES C[C@@H]1CC(=O)Nc2ncnc(N3CCC(CC3)c3nc(cn3CCN3CCCC3)C(F)(F)F)c12
InChI Key InChIKey=WABHLXQVOYVYTI-OAHLLOKOSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50271975
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 876nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant ROCK2 (11 to 552 residues) expressed in insect cells using RFARKGSLRQKNV substrate incubated for 60 ...More data for this Ligand-Target Pair