BDBM50272072 (E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-yl)acetamide::CHEMBL503074

SMILES CC(=O)Nc1nccc(\C=C\c2c(nc3sccn23)-c2ccccc2)n1

InChI Key InChIKey=VZDFUZNYSXFDFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272072   

TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272072((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272072((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272072((E/Z)-N-(4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed