BDBM50272289 CHEMBL500146::Methyl 5-(6-methoxynaphthalen-2-yl)pyridine-3-carboxylate

SMILES COC(=O)c1cncc(c1)-c1ccc2cc(OC)ccc2c1

InChI Key InChIKey=CBEZYLKPJKSBRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272289   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272289(Methyl 5-(6-methoxynaphthalen-2-yl)pyridine-3-carb...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272289(Methyl 5-(6-methoxynaphthalen-2-yl)pyridine-3-carb...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed