BDBM50272486 CHEMBL498527::N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4-dihydroquinoline-3-carboxamide

SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(Sc3ccccc3)cc12

InChI Key

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272486   

TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor transfected in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by Competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by Competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50272486(N-(Adamant-1-yl)-4-oxo-1-pentyl-7-(phenylthio)-1,4...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor transfected in HEK cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed