BDBM50272559 3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbamoyl)-3-carbamoyl-propylcarbamoyl]-2-hydroxy-propylsulfamoyl}-methyl)-benzoic acid::CHEMBL506502

SMILES C[C@@H](O)[C@H](NS(=O)(=O)Cc1cccc(c1)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=BVRYSOCIONUZJI-RFVSGWPVSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50272559   

TargetCoagulation factor VII(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272559(3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbam...)
Affinity DataKi:  74nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272559(3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbam...)
Affinity DataKi:  259nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272559(3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbam...)
Affinity DataKi:  1.47E+4nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272559(3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbam...)
Affinity DataKi:  4.55E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XII(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272559(3-({(1S,2R)-1-[(S)-1-(4-Carbamimidoyl-benzylcarbam...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human factor 12aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed