BDBM50272638 2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methyl-N,N-dipropylpyrimidin-5-amine::CHEMBL525716

SMILES CCCN(CCC)c1c(C)nc(nc1OC)-c1c(OC)cc(Cl)cc1OC

InChI Key InChIKey=LFRGIXCYYJTHTK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272638   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50272638(2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methy...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at CRF1 receptor expressed in mouse AtT20 cells assessed as inhibition of sauvagine-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed