BDBM50272652 CHEMBL497492::N-methyl((3R,4S)-4-(2-(methylthio)phenoxy)-3,4-dihydro-1H-isochromen-3-yl)methanamine

SMILES CNC[C@H]1OCc2ccccc2[C@@H]1Oc1ccccc1SC

InChI Key InChIKey=AKOJURNFNIUCOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272652   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272652(N-methyl((3R,4S)-4-(2-(methylthio)phenoxy)-3,4-dih...)
Affinity DataIC50: 45nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272652(N-methyl((3R,4S)-4-(2-(methylthio)phenoxy)-3,4-dih...)
Affinity DataIC50: 640nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272652(N-methyl((3R,4S)-4-(2-(methylthio)phenoxy)-3,4-dih...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed