BDBM50272720 CHEMBL498686::N-methyl((1R,2R)-1-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-yl)methanamine

SMILES CNC[C@H]1CCc2ccccc2[C@@H]1Oc1ccccc1C

InChI Key InChIKey=CBIWVBLPTDWHKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272720   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272720(N-methyl((1R,2R)-1-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 180nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272720(N-methyl((1R,2R)-1-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272720(N-methyl((1R,2R)-1-(o-tolyloxy)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed