BDBM50272722 ((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine::CHEMBL498687

SMILES CCc1ccccc1O[C@@H]1[C@H](CNC)OCc2ccccc12

InChI Key InChIKey=OBPAJKUDOWNRDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272722   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272722(((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochro...)
Affinity DataIC50: 15nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272722(((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochro...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272722(((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed