BDBM50272727 ((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine::CHEMBL497845

SMILES CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1cc(F)ccc1C

InChI Key InChIKey=TUPKUZCHBMCYHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272727   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272727(((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272727(((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272727(((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed