BDBM50272747 ((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine::CHEMBL452429

SMILES CNC[C@H]1COc2ccccc2[C@H]1Oc1ccccc1Cl

InChI Key InChIKey=DZEOBMAMUUMJNJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272747   

TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272747(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chrome...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant CYP32D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272747(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chrome...)
Affinity DataIC50: 230nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272747(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chrome...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272747(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chrome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed