BDBM50272808 CHEMBL497863::N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[(2,2,2-trifluoro-ethyl)-hydrazonomethyl]-pyrimidine-4,6-diamine
SMILES Nc1ncnc(Nc2ccc3n(Cc4cccc(F)c4)ncc3c2)c1CN=NCC(F)(F)F
InChI Key InChIKey=WAEKMWDUWGUADN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50272808
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human ErbB2More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of human ErB2 phosphorylation in human SKBR3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human EGFR expressed in SF9 cellsMore data for this Ligand-Target Pair