BDBM50272820 CHEMBL498664::N-(1H-indol-4-yl)-1-(3-(trifluoromethyl)phenyl)piperidine-4-carboxamide

SMILES O=C(Nc1cccc2[nH]ccc12)C1CCN(c2cccc(C(F)(F)F)c2)CC1

InChI Key InChIKey=RWHPXEFGRCUQEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272820   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272820BDBM50272820(N-(1H-indol-4-yl)-1-(3-(trifluoromethyl)phenyl)pip...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed