BDBM50272840 5-[((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydro-2-naphthalenyl)oxy]-2-thiophenecarboxylic Acid::CHEMBL497280

SMILES O[C@@H](CN[C@H]1CCc2ccc(Oc3ccc(s3)C(O)=O)cc2C1)c1cccc(Cl)c1

InChI Key InChIKey=ICMKXYZWRPPWMR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272840   

TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272840(5-[((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272840(5-[((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272840(5-[((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed