BDBM50273539 CHEMBL4125815::US11535607, Example 50-6

SMILES ONC(=O)c1cccc2CCN(Cc12)c1nc2ccccc2[nH]1

InChI Key InChIKey=ACQXBOFJJPVJDR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273539   

TargetHistone deacetylase 6(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273539(CHEMBL4125815 | US11535607, Example 50-6)
Affinity DataIC50:  82nMAssay Description:Inhibition of full length recombinant human HDAC6 using fluorescent-labeled peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273539(CHEMBL4125815 | US11535607, Example 50-6)
Affinity DataIC50: <500nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50273539(CHEMBL4125815 | US11535607, Example 50-6)
Affinity DataIC50: >1.00E+3nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50273539(CHEMBL4125815 | US11535607, Example 50-6)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed