BDBM50273822 5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one::CHEMBL458086

SMILES C[C@H](NC1=NC(=O)C(C)(S1)c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=MIGKHDFDKUOWGG-FAQQKDIKSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273822   

LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed