BDBM50273941 CHEMBL456196::iso-Propyl-4-[1-(2-fuluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydropyridine-1(2H)-carboxylate

SMILES CC(C)OC(=O)N1CCC(=CC1)c1nnn(c1C)-c1cccnc1F

InChI Key InChIKey=OVURPMRKVYGKGC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273941   

TargetMetabotropic glutamate receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273941(CHEMBL456196 | iso-Propyl-4-[1-(2-fuluoropyridine-...)
Affinity DataIC50:  7.20nMAssay Description:Antagonist activity at human mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273941(CHEMBL456196 | iso-Propyl-4-[1-(2-fuluoropyridine-...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Mouse)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273941(CHEMBL456196 | iso-Propyl-4-[1-(2-fuluoropyridine-...)
Affinity DataIC50:  3.30nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed