BDBM50274056 CHEMBL521467::N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester

SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC(C)=O)C(C)C

InChI Key InChIKey=NRWCYEVIDSSFKZ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274056   

TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi:  8.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed