BDBM50274156 CHEMBL4128368

SMILES Fc1cc(\C=C\c2ccc(cc2)N2CCN(CC2)S(=O)(=O)C(F)(F)F)cc(c1)-c1ccncc1

InChI Key InChIKey=YWPJEUFWPODNLT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274156   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50274156(CHEMBL4128368)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using [21-3H]17alpha-hydroxypregnenolone as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetAromatase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50274156(CHEMBL4128368)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP19 (unknown origin) by Becton Dickinson aromatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50274156(CHEMBL4128368)
Affinity DataIC50: 9.36E+3nMAssay Description:Inhibition of human CYP3A4 using testosterone as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed