BDBM50274785 1-(3-bromophenyl)-N-isobutyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide::CHEMBL464600

SMILES CC(C)CNC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O

InChI Key InChIKey=FRKIIAMJXUEZSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274785   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50274785(1-(3-bromophenyl)-N-isobutyl-4-oxo-1,4-dihydro-1,8...)
Affinity DataIC50:  3.18E+4nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50274785(1-(3-bromophenyl)-N-isobutyl-4-oxo-1,4-dihydro-1,8...)
Affinity DataIC50:  3.54nMAssay Description:Intrinsic inhibition of GST-fused human PDE4A expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed