BDBM50274893 (Z)-5-(Naphthalen-2'-ylmethylene)thiazolidine-2,4-dione::CHEMBL457715

SMILES OC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1

InChI Key InChIKey=YZXMJWJVDAPREH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274893   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50274893((Z)-5-(Naphthalen-2'-ylmethylene)thiazolidine-2,4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) using GS-2 peptide substrate incubated for 30 mins by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 2(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274893((Z)-5-(Naphthalen-2'-ylmethylene)thiazolidine-2,4-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed