BDBM50274936 (Z)-6-Methyl-1-((5-phenylthiophen-2-yl)methylene)-1H-pyrrolo[3,4-c]pyridine-3,4(2H,5H)-dione::CHEMBL515504

SMILES Cc1cc2\C(NC(=O)c2c(=O)[nH]1)=C\c1ccc(s1)-c1ccccc1

InChI Key InChIKey=VZRYWVSKJDTEPW-GDNBJRDFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274936   

TargetPerforin-1(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50274936((Z)-6-Methyl-1-((5-phenylthiophen-2-yl)methylene)-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed