BDBM50275090 (1H-Benzoimidazol-2-yl)-(6,7-dichloro-1,2,3,4-tetrahydronaphthalen-1-yl)amine::CHEMBL511710
SMILES Clc1cc2CCCC(Nc3nc4ccccc4[nH]3)c2cc1Cl
InChI Key InChIKey=JHLGZRSIUIFADK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50275090
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataKd: 9.10nMAssay Description:Inhibition of Wistar rat recombinant SK3 channel expressed in HEK293 cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataEC50: 1.81E+3nMAssay Description:Inhibition of wild type human SK3 channel expressed in HEK293 cells assessed as Ca2+ sensitivity by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataKd: 47nMAssay Description:Inhibition of human SK2 channel by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataKd: 60nMAssay Description:Inhibition of human SK3 channel by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataKd: 54nMAssay Description:Inhibition of human SK1 channel by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Inhibition of human SK3 channel expressed in HEK293 cells assessed as Ca2+ induced current after drug wash out by whole cell patch clamp technique in...More data for this Ligand-Target Pair