BDBM50275836 3-ethylthio-5-ethyl-2-methyl-4-propyl-6-(3-chlorophenyl)-1,4-(+)-dihydropyridine-3,5-dicarboxylate::CHEMBL323042

SMILES CCCC1\C(=C(/O)SCC)C(C)=NC(=C1C(=O)OCC)c1ccccc1

InChI Key InChIKey=DQAPCAIOIAMAQE-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275836   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275836(3-ethylthio-5-ethyl-2-methyl-4-propyl-6-(3-chlorop...)
Affinity DataKi:  2.17E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275836(3-ethylthio-5-ethyl-2-methyl-4-propyl-6-(3-chlorop...)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonist-enhancing activity at TRPV1 receptor in E15 rat primary dorsal root ganglion cells assessed as capsaicin-induced 45Ca2+ influx by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275836(3-ethylthio-5-ethyl-2-methyl-4-propyl-6-(3-chlorop...)
Affinity DataEC50:  2.24E+4nMAssay Description:Agonist-enhancing activity in epsilon-epitope tagged TRPV1 receptor expressed in mouse NIH3T3 cells assessed as capsaicin-induced 45Ca2+ influx by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed