BDBM50276855 CHEMBL4168618

SMILES CN1CCC(Nc2ccc(-c3n[nH]c4c3CN(S(=O)(=O)c3c(Cl)cccc3Cl)CC4)cc2)CC1

InChI Key InChIKey=QKAOHFAINNLQDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276855   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50276855BDBM50276855(CHEMBL4168618)
Affinity DataIC50: 68nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50276855BDBM50276855(CHEMBL4168618)
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant human full length FLT3 using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed