BDBM50277296 (S)-6-methyl-N-(2-(phenylamino)-2,3-dihydro-1H-inden-5-yl)-4'-(trifluoromethyl)biphenyl-2-carboxamide::CHEMBL474302

SMILES Cc1cccc(C(=O)Nc2ccc3C[C@@H](Cc3c2)Nc2ccccc2)c1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BJLHXLVEGNRDCK-SANMLTNESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277296   

TargetSmoothened homolog(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277296((S)-6-methyl-N-(2-(phenylamino)-2,3-dihydro-1H-ind...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at mouse Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSmoothened homolog(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277296((S)-6-methyl-N-(2-(phenylamino)-2,3-dihydro-1H-ind...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed