BDBM50277331 (S)-6-methyl-N-(2-((4-methylthiazol-5-yl)methylamino)-2,3-dihydro-1H-inden-5-yl)-4'-(trifluoromethyl)biphenyl-2-carboxamide::CHEMBL474508

SMILES Cc1ncsc1CN[C@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1

InChI Key InChIKey=CVZLQNNEWOTLBK-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277331   

TargetSmoothened homolog(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277331((S)-6-methyl-N-(2-((4-methylthiazol-5-yl)methylami...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSmoothened homolog(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277331((S)-6-methyl-N-(2-((4-methylthiazol-5-yl)methylami...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at mouse Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed