BDBM50277355 CHEMBL4177183

SMILES Nc1nc2[nH]c(CC(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=PFJDDXFAFBODCL-QMMMGPOBSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277355   

TargetBifunctional purine biosynthesis protein ATIC/Thymidylate synthase/Trifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Hebei Medical University

Curated by ChEMBL

LigandBDBM50277355(CHEMBL4177183)Copy SMILESCopy InChI

Affinity DataIC50:  0.0780nMAssay Description:Inhibition of TS/AICARFTase/GARFTase in human KB cells assessed as reduction in cell proliferation in folate free medium after 72 hrs in presence of ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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