BDBM50277733 (2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-oxazol-3-yl)formamido]propanamido]-N-[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]propanamide::CHEMBL484156

SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(C)on1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=RQDDUSFPICWDPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277733   

TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 20s constitutive proteasome beta-5c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50: 238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 20s immunoproteasome beta-5i subunit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed