BDBM50277903 CHEMBL519701::N-((1-(1H-1,2,3-triazol-4-ylsulfonyl)-3-(cyclopropylmethyl)azetidin-3-yl)methyl)-2,4-dichlorobenzamide

SMILES O=C(NCC1(CC2CC2)CN(S(=O)(=O)c2cnn[nH]2)C1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=NBXFRCJXQUHYCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277903   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277903BDBM50277903(N-((1-(1H-1,2,3-triazol-4-ylsulfonyl)-3-(cycloprop...)
Affinity DataIC50: 871nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed