BDBM50278393 CHEMBL4176629

SMILES NS(=O)(=O)c1ccc(cc1)-n1c(SCC(=O)Nc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O

InChI Key InChIKey=JSZXDRLZCGZCFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278393   

TargetEpidermal growth factor receptor(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278393(CHEMBL4176629)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278393(CHEMBL4176629)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed