BDBM50278474 3-Benzyl-8-bromo-5-methoxychromen-2-one::CHEMBL470019

SMILES COc1ccc(Br)c2oc(=O)c(Cc3ccccc3)cc12

InChI Key InChIKey=OPRKTEJKHGVKBY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278474   

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50278474(3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50278474(3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from cannabinoid CB1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetG-protein coupled receptor 55(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50278474(3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed