BDBM50278610 CHEMBL470012::N7-(3-chloro-4-fluorophenyl)-N2-(4-(2-morpholinoethyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES Fc1ccc(Nc2ncnc3nc(Nc4ccc(CCN5CCOCC5)cc4)sc23)cc1Cl

InChI Key InChIKey=YJCSNOSZBTYSKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278610   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278610(CHEMBL470012 | N7-(3-chloro-4-fluorophenyl)-N2-(4-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed