BDBM50279037 CHEMBL4173526

SMILES CS(=O)(=O)c1ccc2n(Cc3ccc(Cl)cc3)c3CCCCc3c2c1

InChI Key InChIKey=KWEQQTKSVSFAKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50279037   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50:  280nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50:  27nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50:  56nMAssay Description:Compound was evaluated for its binding affinity against Toxoplasma gondii purine nucleoside phosphorylase of virulent strain RH (value indicates comp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed