BDBM50279273 CHEMBL4160980

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2cccc(OCCOCCOCCNC(=O)C3CCN(c4ncc(C(=O)Nc5ccc(OC(F)(F)Cl)cc5)cc4-c4ccn[nH]4)C3)c2)cs1)C1CCCCC1

InChI Key InChIKey=ZFKMAJWPPZNUKT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50279273   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279273BDBM50279273(CHEMBL4160980)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279273BDBM50279273(CHEMBL4160980)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279273BDBM50279273(CHEMBL4160980)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279273BDBM50279273(CHEMBL4160980)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed